AMM931-62 [Monoclonal Antibody]
CD20 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   IHC ELISA ICC
Immunogen Range:   A purified recombinant fragment of human CD20 expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   931
Swiss Prot:   P11836
Synonyms:   B1, S7, Bp35, CD20, MS4A2, LEU-16, MGC3969, MS4A1
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.
Caculated MW:   33 kDa.
Observed MW:   Refer to Figures
Applications:   IHC 1:200-1:1000
ICC 1:200-1:1000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information