AMM5657-61
[Monoclonal Antibody]
Proteinase 3 Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | WB ELISA |
| Immunogen Range: | A purified recombinant fragment of human Proteinase 3 expressed in E. Coli |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG1 |
| GENE ID: | 5657 |
| Swiss Prot: | P24158 |
| Synonyms: | PRTN3, ACPA, CANCA |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis. |
| Caculated MW: | 28 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
