AMM4288-61
[Monoclonal Antibody]
KI67 Mouse Monoclonal Antibody
www.yhsbio.com
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Species: |
Mouse |
Applications: |
IHC ELISA |
Immunogen Range: |
A purified recombinant fragment of human KI67 expressed in E. Coli |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 |
GENE ID: |
4288 |
Swiss Prot: |
P46013 |
Synonyms: |
KIA, Ki-67, MKI67 |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Ki67, also known as MKI67, it is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation. |
Caculated MW: |
358 kDa |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:200-1:1000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!