Species: | Mouse |
Applications: | WB ELISA ICC FC |
Immunogen Range: | A purified recombinant fragment of human BLK expressed in E. Coli |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 |
GENE ID: | 640 |
Swiss Prot: | P51451 |
Synonyms: | EC 2.7.10.2B lymphocyte kinasep55-BLK |
Purification: | Affinity chromatography |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response . |
Caculated MW: | 58 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 ICC 1:200-1:1000 FC 1:200-1:400 |
Reacitivity: | Human |