AMM640-61 [Monoclonal Antibody]
BLK Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA ICC FC
Immunogen Range:   A purified recombinant fragment of human BLK expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   640
Swiss Prot:   P51451
Synonyms:   EC 2.7.10.2B lymphocyte kinasep55-BLK
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response .
Caculated MW:   58 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
ICC 1:200-1:1000
FC 1:200-1:400
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information