AMM6850-61
[Monoclonal Antibody]
SYK Mouse Monoclonal Antibody
www.yhsbio.com
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DATASHEET
| Species: |
Mouse |
| Applications: |
WB ELISA |
| Immunogen Range: |
A purified recombinant fragment of human SYK expressed in E. Coli |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG1 |
| GENE ID: |
6850 |
| Swiss Prot: |
P43405 |
| Synonyms: |
EC 2.7.10.2, KSYK, SYK, Spleen tyrosine kinase, kinase Syk |
| Purification: |
Affinity chromatography |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
Syk is a cytoplasmic tyrosine kinase of the SYK family containing two SH2 domains. Plays a central role in the B cell receptor (BCR) response. An upstream activator of the PI3K, PLCgamma2, and Rac/cdc42 pathways in the BCR response. Required for the sequential events of Fc gamma IIa receptor-mediated phagocytosis. Expression highest in murine spleen, heart, mammary gland and thymus. Two splice variant isoforms have been described. |
| Caculated MW: |
72 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!