AMM4292-61 [Monoclonal Antibody]
MLH1 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IHC ELISA ICC
Immunogen Range:   A purified recombinant fragment of human MLH1 expressed in E. Coli
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   4292
Swiss Prot:   P40692
Synonyms:   DNA mismatch repair protein Mlh1, MutL protein homolog 1, COCA2
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
Caculated MW:   85 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
Reacitivity:   Human, Monkey
For research use only. Not intended for diagnostic or therapeutic use!
Additional information