Species: | Mouse |
Applications: | WB ELISA ICC FC |
Immunogen Range: | A purified recombinant fragment of human KDR expressed in E. Coli |
Clonality: | Monoclonal Antibody |
Isotype: | IgG1 |
GENE ID: | 3791 |
Swiss Prot: | P35968 |
Synonyms: | EC 2.7.10.1, FLK1, KDR, VGFR2, VGR2, kinase insert domain receptor, protein-tyrosine kinase receptor Flk-1, vascular endothelial growth factor receptor 2 |
Purification: | Affinity chromatography |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | VEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability. |
Caculated MW: | 152 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 ICC 1:200-1:1000 FC 1:200-1:400 |
Reacitivity: | Human |