ARP6093-61
[Polyclonal Antibody]
ROCK1 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | A synthetic peptide derived from human ROCK1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 6093 |
| Swiss Prot: | Q13464 |
| Synonyms: | MGC131603, MGC43611, p160 ROCK-1, p160-ROCK, p160ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, Rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | ROCK1 Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. |
| Caculated MW: | 160 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
