ARP6416-62
[Polyclonal Antibody]
SEK1/MKK4 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC |
| Immunogen Range: |
A synthetic peptide derived from human SEK1/MKK4 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
6416 |
| Swiss Prot: |
P45985 |
| Synonyms: |
C-JUN N-terminal kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 4, EC 2.7.12.2, JNK activating kinase 1, JNK kinase 1, JNKK, JNKK 1, JNKK1, MAP kinase kinase 4, MAP2K4, MAPK/ERK kinase 4, MAPKK 4, MKK4, MP2K4, PRKMK4, SAPK/ERK |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
MKK4 dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38 but not ERK1 or -2. Mediates cellular responses to various cellular stresses and inflammatory cytokines. Phosphorylation by Akt inhibits MKK4 and suppresses stress-activated signal transduction. |
| Caculated MW: |
44 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:50-1:200
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!