ARP2534-61 [Polyclonal Antibody]
Fyn Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human Fyn
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   2534
Swiss Prot:   P06241
Synonyms:   DKFZp762A223, FA-D2, FA4, FACD, FACD2, FAD, FAD2, FANCD, FANCD2, Fanconi anemia group D2 protein, Fanconi anemia, complementation group D2, FLJ23826, Protein FACD2, type 4 Fanconi pancytopenia
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   FANCD2 Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress.
Caculated MW:   60 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information