Species: | Rabbit |
Applications: | WB IHC IF ICC |
Immunogen Range: | A synthetic peptide derived from human p53 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 7157 |
Swiss Prot: | P04637 |
Synonyms: | Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. |
Caculated MW: | 53 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse, Rat |