Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A synthetic peptide derived from human PDGFR α |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5156 |
Swiss Prot: | P16234 |
Synonyms: | Alpha platelet-derived growth factor receptor precursor, CD140a, PDGF-R-alpha, PDGFR-alpha, PGFRA, kinase PDGFR-alpha |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. |
Caculated MW: | 140 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500 |
Reacitivity: | Human, Mouse, Rat |