ARP7158-61
[Polyclonal Antibody]
53BP1 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide derived from human 53BP1 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
7158 |
| Swiss Prot: |
Q12888 |
| Synonyms: |
p53-binding protein 1, P531, TP53B, TP53BP1, TRP53BP1, Tumor suppressor p53-binding protein 1 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
Binds to the central domain of p53/TP53. May form homooligomers. Interacts with DCLRE1C. Interacts with histone H2AFX and this requires phosphorylation of H2AFX on 'Ser-139'. Interacts with histone H4 that has been dimethylated at 'Lys-20' (H4K20me2). Has low affinity for histone H4 containing monomethylated 'Lys-20' (H4K20me1). |
| Caculated MW: |
214 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000
|
| Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!