Species: | Rabbit |
Applications: | WB IHC IF ICC FC |
Immunogen Range: | A synthetic peptide derived from human MMP-8 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4317 |
Swiss Prot: | P22894 |
Synonyms: | CLG1, COLLAGENASE I, NEUTROPHIL, matrix metalloproteinase 8 (neutrophil collagenase) |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. |
Caculated MW: | 53 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 FC 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |