ARP9846-63 [Polyclonal Antibody]
Gab2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   9846
Swiss Prot:   Q9UQC2
Synonyms:   GRB2-associated-binding protein 2, Growth factor receptor bound protein 2-associated protein 2, GRB2-associated binder 2, pp100, KIAA0571
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Caculated MW:   75 kDa
Observed MW:   Refer to Figures
Applications:   WB 0.736111
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information