ARP3309-62 [Polyclonal Antibody]
GRP78 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A synthetic peptide derived from human GRP78
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   3309
Swiss Prot:   P11021
Synonyms:   BIP, GLUCOSE-REGULATED PROTEIN 78-KD, HEAT-SHOCK 70-KD PROTEIN 5, IMMUNOGLOBULIN HEAVY CHAIN-BINDING PROTEIN, heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   GRP78 a member of the HSP family of molecular chaperones required for endoplasmic reticulum integrity and stress-induced autophagy. Plays a central role in regulating the unfolded protein response (UPR), and is an obligatory component of autophagy in mammalian cells.. May play an important role in cellular adaptation and oncogenic survival. One of the client proteins of GRP78 is protein double-stranded RNA-activated protein-like endoplasmic reticulum kinase (PERK).
Caculated MW:   78 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information