ARP355-61
[Polyclonal Antibody]
FAS Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide derived from human FAS |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
355 |
Swiss Prot: |
P25445 |
Synonyms: |
Apo-1, CD95, FasL receptor, TNFRSF6, TNR6, apoptosis-mediating surface antigen FAS, tumor necrosis factor receptor superfamily member 6 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. |
Caculated MW: |
52 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!