Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A synthetic peptide derived from human DNA PK |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5591 |
Swiss Prot: | P78527 |
Synonyms: | DNA- PKcs, DNA-dependent protein kinase catalytic subunit, DNPK1, EC 2.7.11.1, P460, PRKD, PRKDC, XRCC7, kinase DNA-PK |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. |
Caculated MW: | 450 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500 |
Reacitivity: | Human, Mouse |