ARP958-61 [Polyclonal Antibody]
CD40 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A synthetic peptide derived from human CD40
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   958
Swiss Prot:   P25942
Synonyms:   B-cell surface antigen CD40, Bp50, CD40 antigen, CD40L receptor, CDw40, TNR5, tumor necrosis factor receptor superfamily member 5, TNFRSF5
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
Caculated MW:   31 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information