ARP58-61
[Polyclonal Antibody]
ACTA1 Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB IHC IP |
Immunogen Range: |
A synthetic peptide derived from human ACTA1 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
58 |
Swiss Prot: |
P68133 |
Synonyms: |
ACTA, ASMA, CFTD, MPFD, NEM1, NEM2, NEM3, CFTD1, CFTDM |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. |
Caculated MW: |
42 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!