YRP11411-01 [Polyclonal Antibody]
GIOT1/ZNF461 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human GIOT1/ZNF461 (191-240aa)
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   92283
Swiss Prot:  
Synonyms:   GIOT-1, GIOT 1, Gonadotropin inducible ovary transcription repressor 1, Gonadotropin inducible transcription repressor 1, Gonadotropin-inducible ovary transcription repressor 1, Zinc finger protein 461, ZN461_HUMAN, ZNF461.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   GIOT-1 is a 563 amino acid protein belonging to the Kr??ppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information