ARP4851C-61 [Polyclonal Antibody]
Notch 1 (Cleaved-Val1744) Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human Notch 1 (Cleaved-Val1744)
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   4851
Swiss Prot:   P46531
Synonyms:   NOTC1, NOTCH1, TAN1, hN1, neurogenic locus notch homolog protein 1, neurogenic locus notch homolog protein 1 precursor, notch (Drosophila) homolog 1 (translocation-associated), notch homolog 1, translocation-associated (Drosophila), translocation-associat
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus
Caculated MW:   95 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information