Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A synthetic peptide derived from human Notch 2 (Cleaved-Asp1733) |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4853 |
Swiss Prot: | Q04721 |
Synonyms: | Motch B, NOTC2, NOTCH2, NTC2, Neurogenic locus notch homolog protein 2 precursor, hN2 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Synthesized in the endoplasmic reticulum as an inactive form which is proteolytically cleaved by a furin-like convertase in the trans-Golgi network before it reaches the plasma membrane to yield an active, ligand-accessible form. Cleavage results in a C-terminal fragment N(TM) and a N-terminal fragment N(EC) |
Caculated MW: | 110 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500 |
Reacitivity: | Human, Mouse, Rat |