ARP4853C-61 [Polyclonal Antibody]
NOTCH2 (Cleaved-Ala1734) Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human NOTCH2 (Cleaved-Ala1734)
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   4853
Swiss Prot:   Q04721
Synonyms:   Neurogenic locus notch homolog protein 2 [Precursor], Notch 2, hN2, Notch 2 extracellular truncation, Notch 2 intracellular domain, NOTCH2
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus.
Caculated MW:   110 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information