ARP5422-62
[Polyclonal Antibody]
DNA Polymerase α Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide derived from human DNA Polymerase α |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
5422 |
Swiss Prot: |
P09884 |
Synonyms: |
DNA pol alpha, DNA polymerase alpha catalytic subunit, DPOA, DPOLA, EC 2.7.7.7 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Plays an essential role in the initiation of DNA replication. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, a regulatory subunit POLA2/p70 and two primase subunits PRIM1/p49 and PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. POLA1/p180, a regulatory subunit POLA2/p70 and two primase subunits PRIM1/p49 and PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. |
Caculated MW: |
169 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!