ARP860-62
[Polyclonal Antibody]
RUNX2 Rabbit Polyclonal Antibody
www.yhsbio.com
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DATASHEET
Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide derived from human RUNX2 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
860 |
Swiss Prot: |
Q13950 |
Synonyms: |
Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, CBF-alpha-1, Oncogene AML-3, Osteoblast-specific transcription factor 2, OSF-2, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEA2-alpha |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. |
Caculated MW: |
56 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!