ARP2146-61 [Polyclonal Antibody]
EZH2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human EZH2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   2146
Swiss Prot:   Q15910
Synonyms:   EZH 2 antibodyEZH1 antibodyEZH2 antibodyEZH2_HUMAN antibodyEZH2b antibodyHistone-lysine N-methyltransferase EZH2 antibodyKMT 6 antibodyKMT6 antibodyKMT6A antibody
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Caculated MW:   85 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information