ARP4092-62 [Polyclonal Antibody]
Smad7 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human Smad7
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   4092
Swiss Prot:   O15105
Synonyms:   SMAD 7 antibodySMAD antibodySMAD family member 7 antibodySMAD, mothers against DPP homolog 7 (Drosophila) antibodySMAD, mothers against DPP homolog 7 antibodySMAD6 antibodySmad7 antibody
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation.
Caculated MW:   46 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information