ARP837-61 [Polyclonal Antibody]
Caspase 4 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human Caspase 4
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   837
Swiss Prot:   P49662
Synonyms:   Caspase-4, CASP-4, ICH-2 protease, TX protease, ICE(rel)-II, CASP4, ICH2
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-Asp-|-. Ref.14 Enzyme regulation Inhibited by the effector protein NleF that is produced by pathogenic E.coli; this inhibits apoptosis.
Caculated MW:   43 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information