ARP837-61
[Polyclonal Antibody]
Caspase 4 Rabbit Polyclonal Antibody
www.yhsbio.com
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide derived from human Caspase 4 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
837 |
Swiss Prot: |
P49662 |
Synonyms: |
Caspase-4, CASP-4, ICH-2 protease, TX protease, ICE(rel)-II, CASP4, ICH2 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-Asp-|-. Ref.14
Enzyme regulation
Inhibited by the effector protein NleF that is produced by pathogenic E.coli; this inhibits apoptosis. |
Caculated MW: |
43 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!