ARP5295-62
[Polyclonal Antibody]
PI3 kinase P85α Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB IHC |
| Immunogen Range: |
A synthetic peptide derived from human PI3 kinase P85α |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
5295 |
| Swiss Prot: |
P27986 |
| Synonyms: |
GRB1, P85A, phosphatidylinositol 3-kinase regulatory alpha subunit, PI3-kinase p85-alpha, PI3K, PI3K p85-alpha, ptdIns-3-kinase p85-alpha |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. |
| Caculated MW: |
83 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!