ARP3593-61 [Polyclonal Antibody]
Interleukin 12B Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human Interleukin 12B
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   3593
Swiss Prot:   P29460
Synonyms:   Interleukin-12 subunit beta, IL-12B, IL-12 subunit p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, NK cell stimulatory factor chain 2, NKSF2, IL12B, NKSF2
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines.
Caculated MW:   37 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information