ARP117581-61 [Polyclonal Antibody]
Twist2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   Peptide sequence around aa.26~30(P-K-R-F-G) derived from Human Twist2.
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   117581
Swiss Prot:   Q8WVJ9
Synonyms:   DERMO1, MGC117334, bHLHa39
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
Caculated MW:   18 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:1000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information