ARP9429-61
[Polyclonal Antibody]
ABCG2(CD338) Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
Peptide sequence around aa.160~164( R-I-N-R-V) derived from Human ABCG2(CD338). |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
9429 |
Swiss Prot: |
Q9UNQ0 |
Synonyms: |
BMDP, MRX, ABC15, ABCP, BCRP1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123. |
Caculated MW: |
65-80 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:1000
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!