ARP2931P-62 [Polyclonal Antibody]
Phospho-GSK3 alpha-Ser21 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IP
Immunogen Range:   A synthetic peptide derived from human GSK3 alpha around the phosphorylation site of Serine 21
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   2931
Swiss Prot:   P49840
Synonyms:   DKFZp686D0638, glycogen synthase kinase 3 alpha, Glycogen synthase kinase-3 alpha, GSK-3 alpha, GSK3A
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
Caculated MW:   51 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information