ARP672P-62
[Polyclonal Antibody]
Phospho-BRCA1-Ser1423 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
IHC |
| Immunogen Range: |
A synthetic peptide derived from human BRCA1 around the phosphorylation site of Serine 1423 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
672 |
| Swiss Prot: |
P38398 |
| Synonyms: |
BRCA1, Breast cancer type 1 susceptibility protein, familial breast/ovarian cancer gene 1 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC for BRCA1-associated genome surveillance complex. |
| Caculated MW: |
220 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
IHC 1:50-1:200
|
| Reacitivity: |
Human, Rat |
For research use only. Not intended for diagnostic or therapeutic use!