Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A synthetic peptide derived from human PPARG around the phosphorylation site of Ser112 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 5468 |
Swiss Prot: | P37231 |
Synonyms: | GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. |
Caculated MW: | 57 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 0.180556 |
Reacitivity: | Human, Mouse, Rat |