Species: | Rabbit |
Applications: | WB IF ICC |
Immunogen Range: | A synthetic peptide derived from human IRS-1 around the phosphorylation site of Serine 312 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 3667 |
Swiss Prot: | P35568 |
Synonyms: | IRS-1, IRS1, Insulin receptor substrate-1 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2. |
Caculated MW: | 180 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse, Rat |