ARP3667P-62 [Polyclonal Antibody]
Phospho-IRS-1-Ser312 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF ICC
Immunogen Range:   A synthetic peptide derived from human IRS-1 around the phosphorylation site of Serine 312
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   3667
Swiss Prot:   P35568
Synonyms:   IRS-1, IRS1, Insulin receptor substrate-1
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2.
Caculated MW:   180 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information