ARP5610P-61
[Polyclonal Antibody]
Phospho-PKR-Thr446 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide derived from human PKR around the phosphorylation site of Threonine 446 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
5610 |
Swiss Prot: |
P19525 |
Synonyms: |
EC 2.7.11.1Interferon-inducible RNA-dependent protein kinaseEukaryotic translation initiation factor 2-alpha kinase 2eIF-2A protein kinase 2Protein kinase RNA-activatedPKRp68 kinaseP1/eIF-2A protein kinase |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis. |
Caculated MW: |
74 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!