ARP5610P-61 [Polyclonal Antibody]
Phospho-PKR-Thr446 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human PKR around the phosphorylation site of Threonine 446
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   5610
Swiss Prot:   P19525
Synonyms:   EC 2.7.11.1Interferon-inducible RNA-dependent protein kinaseEukaryotic translation initiation factor 2-alpha kinase 2eIF-2A protein kinase 2Protein kinase RNA-activatedPKRp68 kinaseP1/eIF-2A protein kinase
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.
Caculated MW:   74 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information