Species: | Rabbit |
Applications: | IHC IF ICC |
Immunogen Range: | A synthetic peptide derived from human BCL2 around the phosphorylation site of Threonine 69 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 596 |
Swiss Prot: | P10415 |
Synonyms: | Bcl-2, PPP1R50 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. |
Caculated MW: | 28 kDa |
Observed MW: | Refer to Figures |
Applications: |
IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human |