Species: | Rabbit |
Applications: | WB IHC IF ICC |
Immunogen Range: | A synthetic peptide derived from human Amyloid beta A4 around the phosphorylation site of Threonine 743/668 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 351 |
Swiss Prot: | P05067 |
Synonyms: | A4, AAA, ABETA, ABPP, AD1, AICD-50, AICD-57, AICD-59, AID(50), AID(57), AID(59), Alzheimer disease amyloid protein, amyloid beta (A4) precursor protein, Amyloid beta A4 protein, Amyloid intracellular domain 50, Amyloid intracellular domain 57, app |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | APP a cell surface receptor that influences neurite growth, neuronal adhesion and axonogenesis. Cleaved by secretases to form a number of peptides, some of which bind to the acetyltransferase complex Fe65/TIP60 to promote transcriptional activation. |
Caculated MW: | 140 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse, Rat |