ARP4914P-61 [Polyclonal Antibody]
Phospho-Trk A-Tyr680+Tyr681 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human Trk A around the phosphorylation site of Tyrosine 680+Tyrosine 681
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   4914
Swiss Prot:   P04629
Synonyms:   EC 2.7.10.1, High affinity nerve growth factor receptor precursor, NTRK1, Slow nerve growth factor receptor, TRK, TRK1 transforming tyrosine kinase protein, TRKA, Trk-A, kinase TrkA, p140-TrkAMolecular weight: 87511.17
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Caculated MW:   87 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information