Species: | Rabbit |
Applications: | WB IHC IF ICC |
Immunogen Range: | A synthetic peptide derived from human Abl around the phosphorylation site of Tyrosine 393/412 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 25/27 |
Swiss Prot: | P00519/P42684 |
Synonyms: | EC 2.7.10.2p150c-ABLAbelson murine leukemia viral oncogene homolog 1/EC 2.7.10.2Abelson murine leukemia viral oncogene homolog 2Abelson-related gene proteinTyrosine kinase ARG |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. |
Caculated MW: | 135 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse |