ARP6885P-61
[Polyclonal Antibody]
Phospho-MAP3K7-Thr187 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A synthetic peptide derived from human MAP3K7 around the phosphorylation site of Threonine 187 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
6885 |
Swiss Prot: |
O43318 |
Synonyms: |
EC 2.7.11.25, M3K7, MAP3K7, Mitogen-activated protein kinase kinase kinase 7, TGF-beta- activated kinase 1, Transforming growth factor-beta-activated kinase 1, kinase TAK1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
AK1 a protein kinase of the MLK family. Mediates signal transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. |
Caculated MW: |
60 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!