ARPF009P-62 [Polyclonal Antibody]
Phospho-ERK1/2-Thr202/Tyr204 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human ERK1/2 around the phosphorylation site of Threonine 202/Tyrosine 204
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   5594/5595
Swiss Prot:   P27361/P28482
Synonyms:   ERK-1, ERK1, ERT2, Extracellular signal- regulated kinase 1, Insulin-stimulated MAP2 kinase, kinase ERK1, MAP kinase 1, MAPK 1, MAPK3, Microtubule- associated protein-2 kinase, Mitogen-activated protein kinase 3, MK03, MNK1, p44-ERK1, P44-ERK1, p44-MAPK
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Caculated MW:   42,44 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information