ARP3018-61 [Polyclonal Antibody]
Histone H2B Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC IF ICC
Immunogen Range:   A synthetic peptide derived from human Histone H2B
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   8349/8970
Swiss Prot:   P62807/P06899/Q16778/P57053
Synonyms:   H2B histone family, member S, H2B/s, H2BFS, Histone H2B type F-S, Histone H2B.s
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   H2BFS a core component of the nucleoosome. The nucleosome, a basic organizational unit of chromosomal DNA, is octrameric, consisting of two molecules each of histones H2B, H2A, H3, H4. The octamer wraps approximately 147 bp of DNA. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Caculated MW:   14 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information