Species: | Rabbit |
Applications: | IHC IF ICC |
Immunogen Range: | A synthetic peptide derived from human Histone H2B |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 8349/8970 |
Swiss Prot: | P62807/P06899/Q16778/P57053 |
Synonyms: | H2B histone family, member S, H2B/s, H2BFS, Histone H2B type F-S, Histone H2B.s |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | H2BFS a core component of the nucleoosome. The nucleosome, a basic organizational unit of chromosomal DNA, is octrameric, consisting of two molecules each of histones H2B, H2A, H3, H4. The octamer wraps approximately 147 bp of DNA. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. |
Caculated MW: | 14 kDa |
Observed MW: | Refer to Figures |
Applications: |
IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse |