ARP132243-61 [Polyclonal Antibody]
Histone H1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF ICC
Immunogen Range:   A synthetic peptide derived from human Histone H1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   132243
Swiss Prot:   Q8IZA3
Synonyms:   H1 histone family, member O, oocyte-specific, H1FOO, H1OO, Histone H1oo, MGC50807, Oocyte-specific histone H1, Oocyte-specific linker histone H1, OSH1
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   H1FOO May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Caculated MW:   21 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information