ARP8350-62 [Polyclonal Antibody]
Histone H3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF ICC
Immunogen Range:   A synthetic peptide derived from human Histone H3
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   3020/126961/3021
Swiss Prot:   P68431/Q71DI3/P84243
Synonyms:   H3 histone family, member A, H3/A, H31, H3FA, H3FB, H3FC, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, histone 1, H3a, histone cluster 1, H3a, Histone H3.1
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
Caculated MW:   17 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information