Species: | Rabbit |
Applications: | WB IF ICC |
Immunogen Range: | A synthetic peptide derived from human Nibrin around the phosphorylation site of Sersine 278 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4683 |
Swiss Prot: | O60934 |
Synonyms: | Cell cycle regulatory protein P95, NBN, NBS, NIBRIN, NIJMEGEN BREAKAGE syndrome protein 1, p95-NBS1 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome. |
Caculated MW: | 85 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human |