ARP1557-61 [Polyclonal Antibody]
Cytochrome P450 2C19 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human Cytochrome P450 2C19
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1557
Swiss Prot:   P33261
Synonyms:   Cytochrome P450 2C19, EC 1.14.13.80, (R)-limonene 6-monooxygenase, EC 1.14.13.48, (S)-limonene 6-monooxygenase, EC 1.14.13.49, (S)-limonene 7-monooxygenase, CYPIIC19, P450-11A, Mephenytoin 4-hydroxylase, CYPIIC17, P450-254C, CYP2C19, CP2CJ
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24
Caculated MW:   56 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information