Species: | Rabbit |
Applications: | WB IHC IF ICC |
Immunogen Range: | A synthetic peptide derived from human GRP94 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 7184 |
Swiss Prot: | P14625 |
Synonyms: | 94 kDa glucose-regulated protein, ECGP, Endoplasmin, endothelial cell (HBMEC) glycoprotein, ENPL, glucose regulated protein, 94 kDa, GP96, gp96 homolog, GRP-94, GRP94, Heat shock protein 90 kDa beta member 1, heat shock protein 90kDa beta (Grp94), member |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | GRP94 Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Homodimer; disulfide-linked. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. |
Caculated MW: | 92 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse |